BDBM50274444 (--)-1-{3-Dodecanoyl-2,4,6-trihydroxy-5-[(2S,4S)-7-hydroxy-2-(4-hydroxy-phenyl)-chroman-4-yl]-phenyl}-dodecan-1-one::CHEMBL448124
SMILES: CCCCCCCCCCCC(=O)c1c(O)c([C@H]2C[C@H](Oc3cc(O)ccc23)c2ccc(O)cc2)c(O)c(C(=O)CCCCCCCCCCC)c1O
InChI Key: InChIKey=CEJAYJCUSZHYDS-LFGICVIVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Phospholipase A2 group IIA (Rattus norvegicus) | BDBM50274444 ((--)-1-{3-Dodecanoyl-2,4,6-trihydroxy-5-[(2S,4S)-7...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of rat sPLA2 group 2A | Bioorg Med Chem Lett 18: 5415-9 (2008) Article DOI: 10.1016/j.bmcl.2008.09.041 BindingDB Entry DOI: 10.7270/Q2CJ8DB1 | |||||||||||
More data for this Ligand-Target Pair |