BDBM50274577 2-Methyl-3-(4-[(1-propyl-4-piperidinyl)oxy]phenyl)-4(3H)-quinazolinone::CHEMBL484199

SMILES: CCCN1CCC(CC1)Oc1ccc(cc1)-n1c(C)nc2ccccc2c1=O

InChI Key: InChIKey=JSJYNWJYBPRVNY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50274577 (2-Methyl-3-(4-[(1-propyl-4-piperidinyl)oxy]phenyl)...) Show SMILES CCCN1CCC(CC1)Oc1ccc(cc1)-n1c(C)nc2ccccc2c1=O Show InChI InChI=1S/C23H27N3O2/c1-3-14-25-15-12-20(13-16-25)28-19-10-8-18(9-11-19)26-17(2)24-22-7-5-4-6-21(22)23(26)27/h4-11,20H,3,12-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human cloned histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine-induced [35S]GT...				J Med Chem 51: 6889-901 (2008) Article DOI: 10.1021/jm800569w BindingDB Entry DOI: 10.7270/Q27P8Z60
					More data for this Ligand-Target Pair