BDBM50274578 3-(4-[(1-Butyl-4-piperidinyl)oxy]phenyl)-2-methyl-4(3H)-quinazolinone::CHEMBL484200

SMILES: CCCCN1CCC(CC1)Oc1ccc(cc1)-n1c(C)nc2ccccc2c1=O

InChI Key: InChIKey=FBQZQGMQBBKOGP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50274578 (3-(4-[(1-Butyl-4-piperidinyl)oxy]phenyl)-2-methyl-...) Show SMILES CCCCN1CCC(CC1)Oc1ccc(cc1)-n1c(C)nc2ccccc2c1=O Show InChI InChI=1S/C24H29N3O2/c1-3-4-15-26-16-13-21(14-17-26)29-20-11-9-19(10-12-20)27-18(2)25-23-8-6-5-7-22(23)24(27)28/h5-12,21H,3-4,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human cloned histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine-induced [35S]GT...				J Med Chem 51: 6889-901 (2008) Article DOI: 10.1021/jm800569w BindingDB Entry DOI: 10.7270/Q27P8Z60
					More data for this Ligand-Target Pair