BDBM50274859 (Z)-3-Amino-5-(biphenyl-2'-ylmethylene)-2-thioxothiazolidin-4-one::CHEMBL511164

SMILES: NN1C(=S)S\C(=C/c2ccccc2-c2ccccc2)C1=O

InChI Key: InChIKey=JQJVMGHZLZXVOS-UVTDQMKNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arylamine N-acetyltransferase 2 (Mus musculus)	BDBM50274859 ((Z)-3-Amino-5-(biphenyl-2'-ylmethylene)-2-thioxoth...) Show SMILES NN1C(=S)S\C(=C/c2ccccc2-c2ccccc2)C1=O Show InChI InChI=1S/C16H12N2OS2/c17-18-15(19)14(21-16(18)20)10-12-8-4-5-9-13(12)11-6-2-1-3-7-11/h1-10H,17H2/b14-10-	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method				Bioorg Med Chem 17: 905-18 (2009) Article DOI: 10.1016/j.bmc.2008.11.032 BindingDB Entry DOI: 10.7270/Q2PZ58Q3
					More data for this Ligand-Target Pair