BDBM50274950 5-(3-phenethylpyrrolidin-3-yl)-1H-indole::CHEMBL504231

SMILES: C(CC1(CCNC1)c1ccc2[nH]ccc2c1)c1ccccc1

InChI Key: InChIKey=IYTYICIRVUHWDC-UHFFFAOYSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50274950 (5-(3-phenethylpyrrolidin-3-yl)-1H-indole | CHEMBL5...) Show SMILES C(CC1(CCNC1)c1ccc2[nH]ccc2c1)c1ccccc1 Show InChI InChI=1S/C20H22N2/c1-2-4-16(5-3-1)8-10-20(11-13-21-15-20)18-6-7-19-17(14-18)9-12-22-19/h1-7,9,12,14,21-22H,8,10-11,13,15H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC Curated by ChEMBL					Assay Description Inhibition of SERT (unknown origin)				Bioorg Med Chem Lett 18: 6062-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.025 BindingDB Entry DOI: 10.7270/Q29886TF
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50274950 (5-(3-phenethylpyrrolidin-3-yl)-1H-indole | CHEMBL5...) Show SMILES C(CC1(CCNC1)c1ccc2[nH]ccc2c1)c1ccccc1 Show InChI InChI=1S/C20H22N2/c1-2-4-16(5-3-1)8-10-20(11-13-21-15-20)18-6-7-19-17(14-18)9-12-22-19/h1-7,9,12,14,21-22H,8,10-11,13,15H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC Curated by ChEMBL					Assay Description Inhibition of NET (unknown origin)				Bioorg Med Chem Lett 18: 6062-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.025 BindingDB Entry DOI: 10.7270/Q29886TF
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50274950 (5-(3-phenethylpyrrolidin-3-yl)-1H-indole | CHEMBL5...) Show SMILES C(CC1(CCNC1)c1ccc2[nH]ccc2c1)c1ccccc1 Show InChI InChI=1S/C20H22N2/c1-2-4-16(5-3-1)8-10-20(11-13-21-15-20)18-6-7-19-17(14-18)9-12-22-19/h1-7,9,12,14,21-22H,8,10-11,13,15H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC Curated by ChEMBL					Assay Description Inhibition of DAT (unknown origin)				Bioorg Med Chem Lett 18: 6062-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.025 BindingDB Entry DOI: 10.7270/Q29886TF
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50274950 (5-(3-phenethylpyrrolidin-3-yl)-1H-indole | CHEMBL5...) Show SMILES C(CC1(CCNC1)c1ccc2[nH]ccc2c1)c1ccccc1 Show InChI InChI=1S/C20H22N2/c1-2-4-16(5-3-1)8-10-20(11-13-21-15-20)18-6-7-19-17(14-18)9-12-22-19/h1-7,9,12,14,21-22H,8,10-11,13,15H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin) by fluorescence based assay				Bioorg Med Chem Lett 18: 6062-6 (2008) Article DOI: 10.1016/j.bmcl.2008.10.025 BindingDB Entry DOI: 10.7270/Q29886TF
					More data for this Ligand-Target Pair