BDBM50275167 CHEMBL458114::N-(5-chloro-2-methoxyphenyl)-2-hydroxy-3-nitro-benzamide::cid_186169

SMILES: COc1ccc(Cl)cc1NC(=O)c1cccc(c1O)[N+]([O-])=O

InChI Key: InChIKey=SXKNMJHRHWIFCI-UHFFFAOYSA-N

Data: 1 KI  2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thermolysin (Bacillus thermoproteolyticus)	BDBM50275167 (CHEMBL458114 | N-(5-chloro-2-methoxyphenyl)-2-hydr...) Show SMILES COc1ccc(Cl)cc1NC(=O)c1cccc(c1O)[N+]([O-])=O Show InChI InChI=1S/C14H11ClN2O5/c1-22-12-6-5-8(15)7-10(12)16-14(19)9-3-2-4-11(13(9)18)17(20)21/h2-7,18H,1H3,(H,16,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.14E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tromsø Curated by ChEMBL					Assay Description Inhibition of Bacillus thermoproteolyticus thermolysin				J Med Chem 52: 48-61 (2009) Article DOI: 10.1021/jm8008019 BindingDB Entry DOI: 10.7270/Q28P60BR
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50275167 (CHEMBL458114 | N-(5-chloro-2-methoxyphenyl)-2-hydr...) Show SMILES COc1ccc(Cl)cc1NC(=O)c1cccc(c1O)[N+]([O-])=O Show InChI InChI=1S/C14H11ClN2O5/c1-22-12-6-5-8(15)7-10(12)16-14(19)9-3-2-4-11(13(9)18)17(20)21/h2-7,18H,1H3,(H,16,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.14E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of Tromsø Curated by ChEMBL					Assay Description Inhibition of Bacillus thermoproteolyticus thermolysin				J Med Chem 52: 48-61 (2009) Article DOI: 10.1021/jm8008019 BindingDB Entry DOI: 10.7270/Q28P60BR
					More data for this Ligand-Target Pair
corticotropin releasing factor-binding protein (Homo sapiens (Human))	BDBM50275167 (CHEMBL458114 | N-(5-chloro-2-methoxyphenyl)-2-hydr...) Show SMILES COc1ccc(Cl)cc1NC(=O)c1cccc(c1O)[N+]([O-])=O Show InChI InChI=1S/C14H11ClN2O5/c1-22-12-6-5-8(15)7-10(12)16-14(19)9-3-2-4-11(13(9)18)17(20)21/h2-7,18H,1H3,(H,16,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair
corticotropin releasing factor-binding protein (Homo sapiens (Human))	BDBM50275167 (CHEMBL458114 | N-(5-chloro-2-methoxyphenyl)-2-hydr...) Show SMILES COc1ccc(Cl)cc1NC(=O)c1cccc(c1O)[N+]([O-])=O Show InChI InChI=1S/C14H11ClN2O5/c1-22-12-6-5-8(15)7-10(12)16-14(19)9-3-2-4-11(13(9)18)17(20)21/h2-7,18H,1H3,(H,16,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2NC5ZS3
					More data for this Ligand-Target Pair