BDBM50275757 4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile::CHEMBL486371

SMILES: CN1CCN(CCCOc2cc3ncc(C#N)c(Nc4ccc5nc(N)sc5c4)c3cc2C)CC1

InChI Key: InChIKey=HMGYAOFKBQVVQM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50275757 (4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(3...) Show SMILES CN1CCN(CCCOc2cc3ncc(C#N)c(Nc4ccc5nc(N)sc5c4)c3cc2C)CC1 Show InChI InChI=1S/C26H29N7OS/c1-17-12-20-22(14-23(17)34-11-3-6-33-9-7-32(2)8-10-33)29-16-18(15-27)25(20)30-19-4-5-21-24(13-19)35-26(28)31-21/h4-5,12-14,16H,3,6-11H2,1-2H3,(H2,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of iNOS in mouse ANA1 cells				Bioorg Med Chem Lett 18: 6206-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.006 BindingDB Entry DOI: 10.7270/Q2K0743J
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50275757 (4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(3...) Show SMILES CN1CCN(CCCOc2cc3ncc(C#N)c(Nc4ccc5nc(N)sc5c4)c3cc2C)CC1 Show InChI InChI=1S/C26H29N7OS/c1-17-12-20-22(14-23(17)34-11-3-6-33-9-7-32(2)8-10-33)29-16-18(15-27)25(20)30-19-4-5-21-24(13-19)35-26(28)31-21/h4-5,12-14,16H,3,6-11H2,1-2H3,(H2,28,31)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.6	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of cSrc (unknown origin)				Bioorg Med Chem Lett 18: 6206-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.006 BindingDB Entry DOI: 10.7270/Q2K0743J
					More data for this Ligand-Target Pair