BDBM50275796 5-chloro-N-(2-methoxybenzyl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL443165

SMILES: COc1ccccc1CNc1cc(Cl)nc2ccnn12

InChI Key: InChIKey=QHRAEVKEZZEIFJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 3 (KCa2.3) (Homo sapiens (Human))	BDBM50275796 (5-chloro-N-(2-methoxybenzyl)pyrazolo[1,5-a]pyrimid...) Show SMILES COc1ccccc1CNc1cc(Cl)nc2ccnn12 Show InChI InChI=1S/C14H13ClN4O/c1-20-11-5-3-2-4-10(11)9-16-14-8-12(15)18-13-6-7-17-19(13)14/h2-8,16H,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of Kca2.3 channel (unknown origin) expressed in HEK293 cells by thallium flux assay				Bioorg Med Chem Lett 18: 5694-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.026 BindingDB Entry DOI: 10.7270/Q2TM79Z6
					More data for this Ligand-Target Pair