BDBM50276111 2-(4-Phenyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)-1H-benzimidazol-4-Carboxylic Acid Amide::CHEMBL511458

SMILES: CC1(C)NC(C)(C)C(=C1c1nc2c(cccc2[nH]1)C(N)=O)c1ccccc1

InChI Key: InChIKey=MHHZAEHHILULSB-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Rattus norvegicus)	BDBM50276111 (2-(4-Phenyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyr...) Show SMILES CC1(C)NC(C)(C)C(=C1c1nc2c(cccc2[nH]1)C(N)=O)c1ccccc1 |c:7| Show InChI InChI=1S/C22H24N4O/c1-21(2)16(13-9-6-5-7-10-13)17(22(3,4)26-21)20-24-15-12-8-11-14(19(23)27)18(15)25-20/h5-12,26H,1-4H3,(H2,23,27)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Pecs Curated by ChEMBL					Assay Description Inhibition of rat liver PARP1 by scintillation counting				J Med Chem 52: 1619-29 (2009) Article DOI: 10.1021/jm801476y BindingDB Entry DOI: 10.7270/Q29S1QXH
					More data for this Ligand-Target Pair