BDBM50276210 CHEMBL4127879

SMILES: NS(=O)(=O)c1cccc(c1)-c1ccc2nccc(-c3ccncc3F)c2n1

InChI Key: InChIKey=UNTGAQHFGNYSMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50276210 (CHEMBL4127879) Show SMILES NS(=O)(=O)c1cccc(c1)-c1ccc2nccc(-c3ccncc3F)c2n1 Show InChI InChI=1S/C19H13FN4O2S/c20-16-11-22-8-6-14(16)15-7-9-23-18-5-4-17(24-19(15)18)12-2-1-3-13(10-12)27(21,25)26/h1-11H,(H2,21,25,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of full length human ERG expressed in HEK293 cells assessed as reduction in tail current at holding potential of -70 mV after 6 to 7 mins ...				J Med Chem 61: 5692-5703 (2018) Article DOI: 10.1021/acs.jmedchem.8b00648 BindingDB Entry DOI: 10.7270/Q2B85BMK
					More data for this Ligand-Target Pair