BDBM50276289 3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonamide::CHEMBL450994

SMILES: NS(=O)(=O)c1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F

InChI Key: InChIKey=UEPKMFLFRNDVAW-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50276289 (3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonami...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C13H9F4NO2S/c14-12-7-9(3-6-11(12)13(15,16)17)8-1-4-10(5-2-8)21(18,19)20/h1-7H,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay				Bioorg Med Chem Lett 19: 1058-61 (2009) Article DOI: 10.1016/j.bmcl.2009.01.018 BindingDB Entry DOI: 10.7270/Q20R9P8G
					More data for this Ligand-Target Pair				3D Structure (crystal)