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SMILES: NS(=O)(=O)Nc1ccc(cn1)-c1ccc(c(F)c1)C(F)(F)F

InChI Key: InChIKey=HWVUQXIJFQHAKX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276406   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50276406
PNG
(CHEMBL470767 | N-{5-[3-fluoro-4-(trifluoromethyl)p...)
Show SMILES NS(=O)(=O)Nc1ccc(cn1)-c1ccc(c(F)c1)C(F)(F)F
Show InChI InChI=1S/C12H9F4N3O2S/c13-10-5-7(1-3-9(10)12(14,15)16)8-2-4-11(18-6-8)19-22(17,20)21/h1-6H,(H,18,19)(H2,17,20,21)
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n/an/a 40n/an/an/an/an/an/a



University of Shizuoka

Curated by ChEMBL


Assay Description
Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay

Bioorg Med Chem Lett 19: 1058-61 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.018
BindingDB Entry DOI: 10.7270/Q20R9P8G
More data for this
Ligand-Target Pair