BDBM50276483 1-(2,6-diisopropylphenyl)-3-((4-(3-methoxyphenyl)-1-phenylpiperidin-4-yl)methyl)urea::CHEMBL459999::N-(2,6-Diisopropylphenyl)-N'-{[4-(3-methoxyphenyl)-1-phenylpiperidin-4-yl]methyl}urea

SMILES: COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(CC1)c1ccccc1

InChI Key: InChIKey=IYHBUYICNSDGBE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50276483 (1-(2,6-diisopropylphenyl)-3-((4-(3-methoxyphenyl)-...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(CC1)c1ccccc1 Show InChI InChI=1S/C32H41N3O2/c1-23(2)28-15-10-16-29(24(3)4)30(28)34-31(36)33-22-32(25-11-9-14-27(21-25)37-5)17-19-35(20-18-32)26-12-7-6-8-13-26/h6-16,21,23-24H,17-20,22H2,1-5H3,(H2,33,34,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...				Bioorg Med Chem 17: 4636-46 (2009) Article DOI: 10.1016/j.bmc.2009.04.059 BindingDB Entry DOI: 10.7270/Q24M94KR
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276483 (1-(2,6-diisopropylphenyl)-3-((4-(3-methoxyphenyl)-...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(CC1)c1ccccc1 Show InChI InChI=1S/C32H41N3O2/c1-23(2)28-15-10-16-29(24(3)4)30(28)34-31(36)33-22-32(25-11-9-14-27(21-25)37-5)17-19-35(20-18-32)26-12-7-6-8-13-26/h6-16,21,23-24H,17-20,22H2,1-5H3,(H2,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair