BDBM50276566 (+/-)-2-(4-chlorophenyl)-N-(2-(dimethylamino)-6,7-dimethoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(2-methoxyethyl)acetamide::CHEMBL459387

SMILES: COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)Cc1ccc(Cl)cc1

InChI Key: InChIKey=RMMUDGAIHYRSFJ-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50276566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50276566 ((+/-)-2-(4-chlorophenyl)-N-(2-(dimethylamino)-6,7-...) Show SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C25H33ClN2O4/c1-27(2)21-11-8-18-15-22(31-4)23(32-5)16-20(18)25(21)28(12-13-30-3)24(29)14-17-6-9-19(26)10-7-17/h6-7,9-10,15-16,21,25H,8,11-14H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>9.00E+4	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Agonist activity at human cloned mu opioid receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50276566 ((+/-)-2-(4-chlorophenyl)-N-(2-(dimethylamino)-6,7-...) Show SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C25H33ClN2O4/c1-27(2)21-11-8-18-15-22(31-4)23(32-5)16-20(18)25(21)28(12-13-30-3)24(29)14-17-6-9-19(26)10-7-17/h6-7,9-10,15-16,21,25H,8,11-14H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	922	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Displacement of [125I]U69593 from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50276566 ((+/-)-2-(4-chlorophenyl)-N-(2-(dimethylamino)-6,7-...) Show SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C25H33ClN2O4/c1-27(2)21-11-8-18-15-22(31-4)23(32-5)16-20(18)25(21)28(12-13-30-3)24(29)14-17-6-9-19(26)10-7-17/h6-7,9-10,15-16,21,25H,8,11-14H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50276566 ((+/-)-2-(4-chlorophenyl)-N-(2-(dimethylamino)-6,7-...) Show SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C25H33ClN2O4/c1-27(2)21-11-8-18-15-22(31-4)23(32-5)16-20(18)25(21)28(12-13-30-3)24(29)14-17-6-9-19(26)10-7-17/h6-7,9-10,15-16,21,25H,8,11-14H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Displacement of [125I]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W
					More data for this Ligand-Target Pair