BDBM50277002 8-(2-(1H-indol-3-yl)ethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol::CHEMBL460854

SMILES: OC1(CC2CCC(C1)N2CCc1c[nH]c2ccccc12)c1ccc(Cl)cc1

InChI Key: InChIKey=NXGXYFWRVCUKFN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50277002 (8-(2-(1H-indol-3-yl)ethyl)-3-(4-chlorophenyl)-8-az...) Show SMILES OC1(CC2CCC(C1)N2CCc1c[nH]c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H25ClN2O/c24-18-7-5-17(6-8-18)23(27)13-19-9-10-20(14-23)26(19)12-11-16-15-25-22-4-2-1-3-21(16)22/h1-8,15,19-20,25,27H,9-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50277002 (8-(2-(1H-indol-3-yl)ethyl)-3-(4-chlorophenyl)-8-az...) Show SMILES OC1(CC2CCC(C1)N2CCc1c[nH]c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H25ClN2O/c24-18-7-5-17(6-8-18)23(27)13-19-9-10-20(14-23)26(19)12-11-16-15-25-22-4-2-1-3-21(16)22/h1-8,15,19-20,25,27H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50277002 (8-(2-(1H-indol-3-yl)ethyl)-3-(4-chlorophenyl)-8-az...) Show SMILES OC1(CC2CCC(C1)N2CCc1c[nH]c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H25ClN2O/c24-18-7-5-17(6-8-18)23(27)13-19-9-10-20(14-23)26(19)12-11-16-15-25-22-4-2-1-3-21(16)22/h1-8,15,19-20,25,27H,9-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	278	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation counting				Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT
					More data for this Ligand-Target Pair