BDBM50277179 CHEMBL4160328

SMILES: O=C(C1CCCCC1)N1CC2C(C1)C1CCC2C=C1

InChI Key: InChIKey=AVIULPKIBHPWHA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50277179 (CHEMBL4160328) Show SMILES O=C(C1CCCCC1)N1CC2C(C1)C1CCC2C=C1 |c:20,THB:9:10:17.18:15.14,12:11:17.18:15.14| Show InChI InChI=1S/C17H25NO/c19-17(14-4-2-1-3-5-14)18-10-15-12-6-7-13(9-8-12)16(15)11-18/h6-7,12-16H,1-5,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...				Eur J Med Chem 139: 412-428 (2017) Article DOI: 10.1016/j.ejmech.2017.08.003 BindingDB Entry DOI: 10.7270/Q2JM2D5R
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 2 (Homo sapiens (Human))	BDBM50277179 (CHEMBL4160328) Show SMILES O=C(C1CCCCC1)N1CC2C(C1)C1CCC2C=C1 |c:20,THB:9:10:17.18:15.14,12:11:17.18:15.14| Show InChI InChI=1S/C17H25NO/c19-17(14-4-2-1-3-5-14)18-10-15-12-6-7-13(9-8-12)16(15)11-18/h6-7,12-16H,1-5,8-11H2	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysis				Eur J Med Chem 139: 412-428 (2017) Article DOI: 10.1016/j.ejmech.2017.08.003 BindingDB Entry DOI: 10.7270/Q2JM2D5R
					More data for this Ligand-Target Pair