BDBM50277202 CHEMBL4174368

SMILES: O=C(C1CCCCC1)N1CC2C3CCC(C3)C2C1

InChI Key: InChIKey=VJMSNBQMSAFRGS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50277202 (CHEMBL4174368) Show SMILES O=C(C1CCCCC1)N1CC2C3CCC(C3)C2C1 |TLB:9:10:12.13:15,17:16:12.13:15| Show InChI InChI=1S/C16H25NO/c18-16(11-4-2-1-3-5-11)17-9-14-12-6-7-13(8-12)15(14)10-17/h11-15H,1-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...				Eur J Med Chem 139: 412-428 (2017) Article DOI: 10.1016/j.ejmech.2017.08.003 BindingDB Entry DOI: 10.7270/Q2JM2D5R
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 2 (Homo sapiens (Human))	BDBM50277202 (CHEMBL4174368) Show SMILES O=C(C1CCCCC1)N1CC2C3CCC(C3)C2C1 |TLB:9:10:12.13:15,17:16:12.13:15| Show InChI InChI=1S/C16H25NO/c18-16(11-4-2-1-3-5-11)17-9-14-12-6-7-13(8-12)15(14)10-17/h11-15H,1-10H2	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysis				Eur J Med Chem 139: 412-428 (2017) Article DOI: 10.1016/j.ejmech.2017.08.003 BindingDB Entry DOI: 10.7270/Q2JM2D5R
					More data for this Ligand-Target Pair