null

SMILES: C(CN1CCCC(C1)c1ccnc(NC2CC2)n1)C1Cc2ccccc2C1

InChI Key: InChIKey=OTGGRKWIRVAPBH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50277211 (CHEMBL475090 | N-cyclopropyl-4-(1-(2-(2,3-dihydro-...) Show SMILES C(CN1CCCC(C1)c1ccnc(NC2CC2)n1)C1Cc2ccccc2C1 Show InChI InChI=1S/C23H30N4/c1-2-5-19-15-17(14-18(19)4-1)10-13-27-12-3-6-20(16-27)22-9-11-24-23(26-22)25-21-7-8-21/h1-2,4-5,9,11,17,20-21H,3,6-8,10,12-16H2,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	42.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor				Bioorg Med Chem Lett 19: 1159-63 (2009) Article DOI: 10.1016/j.bmcl.2008.12.087 BindingDB Entry DOI: 10.7270/Q29886VW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50277211 (CHEMBL475090 | N-cyclopropyl-4-(1-(2-(2,3-dihydro-...) Show SMILES C(CN1CCCC(C1)c1ccnc(NC2CC2)n1)C1Cc2ccccc2C1 Show InChI InChI=1S/C23H30N4/c1-2-5-19-15-17(14-18(19)4-1)10-13-27-12-3-6-20(16-27)22-9-11-24-23(26-22)25-21-7-8-21/h1-2,4-5,9,11,17,20-21H,3,6-8,10,12-16H2,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human 5HT1A receptor expressed in CHO cells by FLIPR				Bioorg Med Chem Lett 19: 1159-63 (2009) Article DOI: 10.1016/j.bmcl.2008.12.087 BindingDB Entry DOI: 10.7270/Q29886VW
					More data for this Ligand-Target Pair