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SMILES: OC(CN1C(CCc2c1cccc2-c1cccnc1)c1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F

InChI Key: InChIKey=MKGWPAABDULLPM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277492   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM50277492
PNG
(1,1,1-trifluoro-3-(5-(pyridin-3-yl)-2-(3-(1,1,2,2-...)
Show SMILES OC(CN1C(CCc2c1cccc2-c1cccnc1)c1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F
Show InChI InChI=1S/C25H21F7N2O2/c26-23(27)25(31,32)36-17-6-1-4-15(12-17)20-10-9-19-18(16-5-3-11-33-13-16)7-2-8-21(19)34(20)14-22(35)24(28,29)30/h1-8,11-13,20,22-23,35H,9-10,14H2
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Article
PubMed
n/an/a>3.00E+3n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human plasma derived CETP

Bioorg Med Chem Lett 19: 2456-60 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.051
BindingDB Entry DOI: 10.7270/Q2W37W6T
More data for this
Ligand-Target Pair