BDBM50277615 1-(5-tert-butyl-2-methoxyphenyl)-3-(4-(6-(morpholinomethyl)pyridin-3-yl)naphthalen-1-yl)urea::CHEMBL523978

SMILES: COc1ccc(cc1NC(=O)Nc1ccc(-c2ccc(CN3CCOCC3)nc2)c2ccccc12)C(C)(C)C

InChI Key: InChIKey=TVJZPCWJLIDBMN-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50277615 (1-(5-tert-butyl-2-methoxyphenyl)-3-(4-(6-(morpholi...) Show SMILES COc1ccc(cc1NC(=O)Nc1ccc(-c2ccc(CN3CCOCC3)nc2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C32H36N4O3/c1-32(2,3)23-10-14-30(38-4)29(19-23)35-31(37)34-28-13-12-25(26-7-5-6-8-27(26)28)22-9-11-24(33-20-22)21-36-15-17-39-18-16-36/h5-14,19-20H,15-18,21H2,1-4H3,(H2,34,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceutical Curated by ChEMBL					Assay Description Binding affinity to p38alpha (unknown origin) by exchange curve binding kinetic analysis				Bioorg Med Chem Lett 19: 2386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.03.104 BindingDB Entry DOI: 10.7270/Q22N525R
					More data for this Ligand-Target Pair