BDBM50277634 2-(3-(7-hydroxy-5-methyl-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]quinoxalin-3-yl)propanamido)benzoic acid::CHEMBL484605

SMILES: Cn1c2cc(O)ccc2n2nnc(CCC(=O)Nc3ccccc3C(O)=O)c2c1=O

InChI Key: InChIKey=AXLXHCUJAXCMJR-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50277634 (2-(3-(7-hydroxy-5-methyl-4-oxo-4,5-dihydro-[1,2,3]...) Show SMILES Cn1c2cc(O)ccc2n2nnc(CCC(=O)Nc3ccccc3C(O)=O)c2c1=O Show InChI InChI=1S/C20H17N5O5/c1-24-16-10-11(26)6-8-15(16)25-18(19(24)28)14(22-23-25)7-9-17(27)21-13-5-3-2-4-12(13)20(29)30/h2-6,8,10,26H,7,9H2,1H3,(H,21,27)(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assay				J Med Chem 52: 2587-602 (2009) Article DOI: 10.1021/jm900151e BindingDB Entry DOI: 10.7270/Q2RJ4JDG
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50277634 (2-(3-(7-hydroxy-5-methyl-4-oxo-4,5-dihydro-[1,2,3]...) Show SMILES Cn1c2cc(O)ccc2n2nnc(CCC(=O)Nc3ccccc3C(O)=O)c2c1=O Show InChI InChI=1S/C20H17N5O5/c1-24-16-10-11(26)6-8-15(16)25-18(19(24)28)14(22-23-25)7-9-17(27)21-13-5-3-2-4-12(13)20(29)30/h2-6,8,10,26H,7,9H2,1H3,(H,21,27)(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human GPR109A expressed in CHO cells				J Med Chem 52: 2587-602 (2009) Article DOI: 10.1021/jm900151e BindingDB Entry DOI: 10.7270/Q2RJ4JDG
					More data for this Ligand-Target Pair