BDBM50277898 (S)-2-methoxy-3-(4-(2-(5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid::CHEMBL484137

SMILES: CO[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccc(cc2)C(F)(F)F)c2ccsc12)C(O)=O

InChI Key: InChIKey=BLSUWVUDRWYROL-NRFANRHFSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50277898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50277898 ((S)-2-methoxy-3-(4-(2-(5-methyl-2-(4-(trifluoromet...) Show SMILES CO[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccc(cc2)C(F)(F)F)c2ccsc12)C(O)=O |r| Show InChI InChI=1S/C25H22F3NO5S/c1-14-19(29-23(34-14)15-3-6-17(7-4-15)25(26,27)28)9-11-33-20-8-5-16(13-21(32-2)24(30)31)22-18(20)10-12-35-22/h3-8,10,12,21H,9,11,13H2,1-2H3,(H,30,31)/t21-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...				Bioorg Med Chem Lett 19: 2468-73 (2009) Article DOI: 10.1016/j.bmcl.2009.03.036 BindingDB Entry DOI: 10.7270/Q2QC03C3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50277898 ((S)-2-methoxy-3-(4-(2-(5-methyl-2-(4-(trifluoromet...) Show SMILES CO[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccc(cc2)C(F)(F)F)c2ccsc12)C(O)=O |r| Show InChI InChI=1S/C25H22F3NO5S/c1-14-19(29-23(34-14)15-3-6-17(7-4-15)25(26,27)28)9-11-33-20-8-5-16(13-21(32-2)24(30)31)22-18(20)10-12-35-22/h3-8,10,12,21H,9,11,13H2,1-2H3,(H,30,31)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in BHK21 cells assessed as SEAP activity by luciferase reporter transactivation assay				Bioorg Med Chem Lett 19: 2468-73 (2009) Article DOI: 10.1016/j.bmcl.2009.03.036 BindingDB Entry DOI: 10.7270/Q2QC03C3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50277898 ((S)-2-methoxy-3-(4-(2-(5-methyl-2-(4-(trifluoromet...) Show SMILES CO[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccc(cc2)C(F)(F)F)c2ccsc12)C(O)=O |r| Show InChI InChI=1S/C25H22F3NO5S/c1-14-19(29-23(34-14)15-3-6-17(7-4-15)25(26,27)28)9-11-33-20-8-5-16(13-21(32-2)24(30)31)22-18(20)10-12-35-22/h3-8,10,12,21H,9,11,13H2,1-2H3,(H,30,31)/t21-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha by luciferase reporter transactivation assay				Bioorg Med Chem Lett 19: 2468-73 (2009) Article DOI: 10.1016/j.bmcl.2009.03.036 BindingDB Entry DOI: 10.7270/Q2QC03C3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50277898 ((S)-2-methoxy-3-(4-(2-(5-methyl-2-(4-(trifluoromet...) Show SMILES CO[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccc(cc2)C(F)(F)F)c2ccsc12)C(O)=O |r| Show InChI InChI=1S/C25H22F3NO5S/c1-14-19(29-23(34-14)15-3-6-17(7-4-15)25(26,27)28)9-11-33-20-8-5-16(13-21(32-2)24(30)31)22-18(20)10-12-35-22/h3-8,10,12,21H,9,11,13H2,1-2H3,(H,30,31)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...				Bioorg Med Chem Lett 19: 2468-73 (2009) Article DOI: 10.1016/j.bmcl.2009.03.036 BindingDB Entry DOI: 10.7270/Q2QC03C3
					More data for this Ligand-Target Pair