BDBM50277944 2,4-dichloro-N-((3-(cyclopropylmethyl)-1-(1-ethyl-1H-1,2,3-triazol-4-ylsulfonyl)azetidin-3-yl)methyl)benzamide::CHEMBL483344

SMILES: CCn1cc(nn1)S(=O)(=O)N1CC(CNC(=O)c2ccc(Cl)cc2Cl)(CC2CC2)C1

InChI Key: InChIKey=XIZPVHWTMPFRPB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50277944 (2,4-dichloro-N-((3-(cyclopropylmethyl)-1-(1-ethyl-...) Show SMILES CCn1cc(nn1)S(=O)(=O)N1CC(CNC(=O)c2ccc(Cl)cc2Cl)(CC2CC2)C1 Show InChI InChI=1S/C19H23Cl2N5O3S/c1-2-25-9-17(23-24-25)30(28,29)26-11-19(12-26,8-13-3-4-13)10-22-18(27)15-6-5-14(20)7-16(15)21/h5-7,9,13H,2-4,8,10-12H2,1H3,(H,22,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation counting				Bioorg Med Chem Lett 19: 2235-9 (2009) Article DOI: 10.1016/j.bmcl.2009.02.102 BindingDB Entry DOI: 10.7270/Q23R0SSZ
					More data for this Ligand-Target Pair