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SMILES: CN(C)CCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1

InChI Key: InChIKey=FKZDWGCWJYVJIH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278287   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 1


(RAT)		BDBM50278287
PNG
(CHEMBL469381 | N4-(2,3-dihydro-1H-inden-2-yl)-N6-(...)
Show SMILES CN(C)CCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1
Show InChI InChI=1S/C20H24N6/c1-26(2)8-7-21-19-11-17-18(12-22-19)23-13-24-20(17)25-16-9-14-5-3-4-6-15(14)10-16/h3-6,11-13,16H,7-10H2,1-2H3,(H,21,22)(H,23,24,25)
PDB

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PC cid
PC sid
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Similars
Article
PubMed
 102n/an/an/an/an/an/an/an/a



Medical Research Council Technology

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...

Bioorg Med Chem Lett 19: 2190-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.106
BindingDB Entry DOI: 10.7270/Q2057FSP
More data for this
Ligand-Target Pair