BDBM50278350 4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidine::CHEMBL2203701::CHEMBL513193

SMILES: FC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1

InChI Key: InChIKey=DGVKMLVLUHANCZ-UHFFFAOYSA-N

Data: 3 KI  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50278350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50278350 (4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...) Show SMILES FC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H31FN2O/c21-19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50278350 (4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...) Show SMILES FC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H31FN2O/c21-19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem Lett 24: 2236-9 (2014) Article DOI: 10.1016/j.bmcl.2014.03.098 BindingDB Entry DOI: 10.7270/Q2MP54TD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50278350 (4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...) Show SMILES FC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H31FN2O/c21-19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cells				Bioorg Med Chem Lett 19: 2172-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.110 BindingDB Entry DOI: 10.7270/Q2H41RBM
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50278350 (4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...) Show SMILES FC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H31FN2O/c21-19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a
ETH Zurich (Swiss Federal Institute of Technology) Curated by ChEMBL					Assay Description Binding affinity to rat brain histamine H3 receptor after 1 hr by gamma counting				Bioorg Med Chem 20: 2889-96 (2012) Article DOI: 10.1016/j.bmc.2012.03.024 BindingDB Entry DOI: 10.7270/Q2JQ1258
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50278350 (4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...) Show SMILES FC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 Show InChI InChI=1S/C20H31FN2O/c21-19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a
ETH Zurich (Swiss Federal Institute of Technology) Curated by ChEMBL					Assay Description Binding affinity to rat histamine H3 receptor low affinity site after 1 hr by Schard plot analysis				Bioorg Med Chem 20: 2889-96 (2012) Article DOI: 10.1016/j.bmc.2012.03.024 BindingDB Entry DOI: 10.7270/Q2JQ1258
					More data for this Ligand-Target Pair