BDBM50278375 4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzyl(phenyl)phosphinic acid::CHEMBL471454

SMILES: Nc1ccc(cc1NC(=O)c1ccc(CP(O)(=O)c2ccccc2)cc1)-c1cccs1

InChI Key: InChIKey=IPWXMLMEBMYQEH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50278375 (4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzyl...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(CP(O)(=O)c2ccccc2)cc1)-c1cccs1 Show InChI InChI=1S/C24H21N2O3PS/c25-21-13-12-19(23-7-4-14-31-23)15-22(21)26-24(27)18-10-8-17(9-11-18)16-30(28,29)20-5-2-1-3-6-20/h1-15H,16,25H2,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 19: 2053-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.009 BindingDB Entry DOI: 10.7270/Q2QV3MDQ
					More data for this Ligand-Target Pair