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SMILES: Oc1ccccc1Oc1ccc(C#N)c(c1)C(F)(F)F

InChI Key: InChIKey=OILQEGDAOXVJJG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50278403 (4-(2-hydroxyphenoxy)-2-(trifluoromethyl)benzonitri...) Show SMILES Oc1ccccc1Oc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C14H8F3NO2/c15-14(16,17)11-7-10(6-5-9(11)8-18)20-13-4-2-1-3-12(13)19/h1-7,19H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced response				Bioorg Med Chem Lett 19: 2176-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.104 BindingDB Entry DOI: 10.7270/Q27P8Z8W
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50278403 (4-(2-hydroxyphenoxy)-2-(trifluoromethyl)benzonitri...) Show SMILES Oc1ccccc1Oc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C14H8F3NO2/c15-14(16,17)11-7-10(6-5-9(11)8-18)20-13-4-2-1-3-12(13)19/h1-7,19H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell system				Bioorg Med Chem Lett 19: 2176-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.104 BindingDB Entry DOI: 10.7270/Q27P8Z8W
					More data for this Ligand-Target Pair