BDBM50278533 CHEMBL470192::N-(2-amino-1-phenylethyl)-5-(1H-pyrrolo[2,3-b]pyridin-3-yl)thiophene-2-carboxamide

SMILES: NCC(NC(=O)c1ccc(s1)-c1c[nH]c2ncccc12)c1ccccc1

InChI Key: InChIKey=XGVJSYKODLTBGE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50278533 (CHEMBL470192 | N-(2-amino-1-phenylethyl)-5-(1H-pyr...) Show SMILES NCC(NC(=O)c1ccc(s1)-c1c[nH]c2ncccc12)c1ccccc1 Show InChI InChI=1S/C20H18N4OS/c21-11-16(13-5-2-1-3-6-13)24-20(25)18-9-8-17(26-18)15-12-23-19-14(15)7-4-10-22-19/h1-10,12,16H,11,21H2,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 19: 2244-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.094 BindingDB Entry DOI: 10.7270/Q24X57PX
					More data for this Ligand-Target Pair