BDBM50278670 CHEMBL4171724

SMILES: OC(=O)CCc1cc(F)c(OCc2c(nsc2C(F)(F)F)-c2ccc(Cl)c(F)c2)c(F)c1

InChI Key: InChIKey=WDBDYYZRGDMJMJ-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 120 (Homo sapiens (Human))	BDBM50278670 (CHEMBL4171724) Show SMILES OC(=O)CCc1cc(F)c(OCc2c(nsc2C(F)(F)F)-c2ccc(Cl)c(F)c2)c(F)c1 Show InChI InChI=1S/C20H12ClF6NO3S/c21-12-3-2-10(7-13(12)22)17-11(19(32-28-17)20(25,26)27)8-31-18-14(23)5-9(6-15(18)24)1-4-16(29)30/h2-3,5-7H,1,4,8H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Janssen Research and Development LLC Curated by ChEMBL					Assay Description Agonist activity at human GPR120 short splice variant expressed in HEK293 cells assessed as increase in intracellular calcium flux incubated for 30 m...				ACS Med Chem Lett 8: 947-952 (2017) Article DOI: 10.1021/acsmedchemlett.7b00233 BindingDB Entry DOI: 10.7270/Q2BV7K4T
					More data for this Ligand-Target Pair
Omega-3 fatty acid receptor 1 (Mus musculus)	BDBM50278670 (CHEMBL4171724) Show SMILES OC(=O)CCc1cc(F)c(OCc2c(nsc2C(F)(F)F)-c2ccc(Cl)c(F)c2)c(F)c1 Show InChI InChI=1S/C20H12ClF6NO3S/c21-12-3-2-10(7-13(12)22)17-11(19(32-28-17)20(25,26)27)8-31-18-14(23)5-9(6-15(18)24)1-4-16(29)30/h2-3,5-7H,1,4,8H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	102	n/a	n/a	n/a	n/a
Janssen Research and Development LLC Curated by ChEMBL					Assay Description Agonist activity at mouse GPR120 by calcium flux assay				ACS Med Chem Lett 8: 947-952 (2017) Article DOI: 10.1021/acsmedchemlett.7b00233 BindingDB Entry DOI: 10.7270/Q2BV7K4T
					More data for this Ligand-Target Pair
G-protein coupled receptor 120 (Homo sapiens (Human))	BDBM50278670 (CHEMBL4171724) Show SMILES OC(=O)CCc1cc(F)c(OCc2c(nsc2C(F)(F)F)-c2ccc(Cl)c(F)c2)c(F)c1 Show InChI InChI=1S/C20H12ClF6NO3S/c21-12-3-2-10(7-13(12)22)17-11(19(32-28-17)20(25,26)27)8-31-18-14(23)5-9(6-15(18)24)1-4-16(29)30/h2-3,5-7H,1,4,8H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a
Janssen Research and Development LLC Curated by ChEMBL					Assay Description Agonist activity at PK-tagged human GPR120 long isoform expressed in CHOK1 cells co-expressing EA-tagged beta-arrestin assessed as beta-gal enzyme co...				ACS Med Chem Lett 8: 947-952 (2017) Article DOI: 10.1021/acsmedchemlett.7b00233 BindingDB Entry DOI: 10.7270/Q2BV7K4T
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50278670 (CHEMBL4171724) Show SMILES OC(=O)CCc1cc(F)c(OCc2c(nsc2C(F)(F)F)-c2ccc(Cl)c(F)c2)c(F)c1 Show InChI InChI=1S/C20H12ClF6NO3S/c21-12-3-2-10(7-13(12)22)17-11(19(32-28-17)20(25,26)27)8-31-18-14(23)5-9(6-15(18)24)1-4-16(29)30/h2-3,5-7H,1,4,8H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Janssen Research and Development LLC Curated by ChEMBL					Assay Description Agonist activity at human GPR40 by calcium flux assay				ACS Med Chem Lett 8: 947-952 (2017) Article DOI: 10.1021/acsmedchemlett.7b00233 BindingDB Entry DOI: 10.7270/Q2BV7K4T
					More data for this Ligand-Target Pair