BDBM50278767 4-bromo-N-(1-(ethylamino)-3-phenylpropan-2-yl)-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide::CHEMBL471059

SMILES: CCNCC(Cc1ccccc1)NC(=O)c1cc(Br)c(s1)-c1ccnc2[nH]ccc12

InChI Key: InChIKey=YGTDSYGYZFQKOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50278767 (4-bromo-N-(1-(ethylamino)-3-phenylpropan-2-yl)-5-(...) Show SMILES CCNCC(Cc1ccccc1)NC(=O)c1cc(Br)c(s1)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H23BrN4OS/c1-2-25-14-16(12-15-6-4-3-5-7-15)28-23(29)20-13-19(24)21(30-20)17-8-10-26-22-18(17)9-11-27-22/h3-11,13,16,25H,2,12,14H2,1H3,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 19: 2244-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.094 BindingDB Entry DOI: 10.7270/Q24X57PX
					More data for this Ligand-Target Pair