BDBM50278991 CHEMBL502022::cis-2-(6-Biphenyl-3-yl-pyridin-3-yl)-5-methyl-octahydro-pyrrolo[3,4-c]pyrrole p-Toluenesulfonate

SMILES: CN1C[C@H]2CN(C[C@H]2C1)c1ccc(nc1)-c1cccc(c1)-c1ccccc1

InChI Key: InChIKey=VKDPCCLZRTXWDV-SZPZYZBQSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278991   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50278991 (CHEMBL502022 | cis-2-(6-Biphenyl-3-yl-pyridin-3-yl...) Show SMILES CN1C[C@H]2CN(C[C@H]2C1)c1ccc(nc1)-c1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C24H25N3/c1-26-14-21-16-27(17-22(21)15-26)23-10-11-24(25-13-23)20-9-5-8-19(12-20)18-6-3-2-4-7-18/h2-13,21-22H,14-17H2,1H3/t21-,22+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A585539 from alpha7 nicotinic acetylcholine receptor in rat brain minus cerebellum membrane				J Med Chem 52: 4126-41 (2009) Article DOI: 10.1021/jm900249k BindingDB Entry DOI: 10.7270/Q2GT5P3R
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50278991 (CHEMBL502022 | cis-2-(6-Biphenyl-3-yl-pyridin-3-yl...) Show SMILES CN1C[C@H]2CN(C[C@H]2C1)c1ccc(nc1)-c1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C24H25N3/c1-26-14-21-16-27(17-22(21)15-26)23-10-11-24(25-13-23)20-9-5-8-19(12-20)18-6-3-2-4-7-18/h2-13,21-22H,14-17H2,1H3/t21-,22+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain minus cerebellum membrane				J Med Chem 52: 4126-41 (2009) Article DOI: 10.1021/jm900249k BindingDB Entry DOI: 10.7270/Q2GT5P3R
					More data for this Ligand-Target Pair