null

SMILES: O=c1cccc2[C@@H]3C[C@@H](CN(Cc4ccncc4)C3)Cn12

InChI Key: InChIKey=ZURWTQIFMLYQTH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50279178 (CHEMBL522410 | N-[(Pyridin-4-yl)methyl]cytisine) Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(Cc4ccncc4)C3)Cn12 |r| Show InChI InChI=1S/C17H19N3O/c21-17-3-1-2-16-15-8-14(11-20(16)17)10-19(12-15)9-13-4-6-18-7-5-13/h1-7,14-15H,8-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	675	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Genova Curated by ChEMBL					Assay Description Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates				J Med Chem 52: 4345-57 (2009) Article DOI: 10.1021/jm900225j BindingDB Entry DOI: 10.7270/Q2K64J03
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50279178 (CHEMBL522410 | N-[(Pyridin-4-yl)methyl]cytisine) Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(Cc4ccncc4)C3)Cn12 |r| Show InChI InChI=1S/C17H19N3O/c21-17-3-1-2-16-15-8-14(11-20(16)17)10-19(12-15)9-13-4-6-18-7-5-13/h1-7,14-15H,8-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Genova Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates				J Med Chem 52: 4345-57 (2009) Article DOI: 10.1021/jm900225j BindingDB Entry DOI: 10.7270/Q2K64J03
					More data for this Ligand-Target Pair