BDBM50279284 (Z)-2-(Ethylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-3,5-dihydro-4H-imidazol-4-one::CHEMBL498716

SMILES: CCNC1=NC(=Cc2c[nH]c3ncccc23)C(=O)N1

InChI Key: InChIKey=GLDLPXUQTGICFM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50279284 ((Z)-2-(Ethylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-y...) Show SMILES CCNC1=NC(=Cc2c[nH]c3ncccc23)C(=O)N1 |w:6.6,t:3| Show InChI InChI=1S/C13H13N5O/c1-2-14-13-17-10(12(19)18-13)6-8-7-16-11-9(8)4-3-5-15-11/h3-7H,2H2,1H3,(H,15,16)(H2,14,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2				J Med Chem 52: 4380-90 (2009) Article DOI: 10.1021/jm900248g BindingDB Entry DOI: 10.7270/Q2FF3S8C
					More data for this Ligand-Target Pair