BDBM50279481 6-(3-(dimethylamino)propyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL488573

SMILES: CN(C)CCCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3ccc12

InChI Key: InChIKey=YZYPLNUVOXFRDU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279481 (6-(3-(dimethylamino)propyl)-9-hydroxypyrrolo[3,4-c...) Show SMILES CN(C)CCCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3ccc12 Show InChI InChI=1S/C19H19N3O3/c1-21(2)8-3-9-22-14-6-4-11(23)10-13(14)16-15(22)7-5-12-17(16)19(25)20-18(12)24/h4-7,10,23H,3,8-9H2,1-2H3,(H,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair