BDBM50279517 9-hydroxy-6-(4-morpholino-4-oxobutyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL520049

SMILES: Oc1ccc2n(CCCC(=O)N3CCOCC3)c3ccc4C(=O)NC(=O)c4c3c2c1

InChI Key: InChIKey=IEMAPJFWPQVOQO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279517 (9-hydroxy-6-(4-morpholino-4-oxobutyl)pyrrolo[3,4-c...) Show SMILES Oc1ccc2n(CCCC(=O)N3CCOCC3)c3ccc4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C22H21N3O5/c26-13-3-5-16-15(12-13)19-17(6-4-14-20(19)22(29)23-21(14)28)25(16)7-1-2-18(27)24-8-10-30-11-9-24/h3-6,12,26H,1-2,7-11H2,(H,23,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair