BDBM50279534 4-(2-chlorophenyl)-9-hydroxy-6-(4-morpholino-4-oxobutyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL519212

SMILES: Oc1ccc2n(CCCC(=O)N3CCOCC3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl

InChI Key: InChIKey=QEHQRRBWGWGIBP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279534 (4-(2-chlorophenyl)-9-hydroxy-6-(4-morpholino-4-oxo...) Show SMILES Oc1ccc2n(CCCC(=O)N3CCOCC3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl Show InChI InChI=1S/C28H24ClN3O5/c29-20-5-2-1-4-17(20)18-15-22-24(26-25(18)27(35)30-28(26)36)19-14-16(33)7-8-21(19)32(22)9-3-6-23(34)31-10-12-37-13-11-31/h1-2,4-5,7-8,14-15,33H,3,6,9-13H2,(H,30,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair