BDBM50279726 9-hydroxy-6-(2-hydroxyethyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL475325

SMILES: OCCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3ccc12

InChI Key: InChIKey=VOHWBQLPPKZDKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279726 (9-hydroxy-6-(2-hydroxyethyl)pyrrolo[3,4-c]carbazol...) Show SMILES OCCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3ccc12 Show InChI InChI=1S/C16H12N2O4/c19-6-5-18-11-3-1-8(20)7-10(11)13-12(18)4-2-9-14(13)16(22)17-15(9)21/h1-4,7,19-20H,5-6H2,(H,17,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair