BDBM50279929 (2Z,6E,10E,14E)-6,11,15,19-Tetramethyl-2-(4-methyl-pent-3-enyl)-icosa-2,6,10,14,18-pentaen-1-ol::CHEMBL312758
SMILES: [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6]-[#8])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]
InChI Key: InChIKey=UFMRPNJEGRFXCQ-SUNBHHBFSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Squalene monooxygenase (Homo sapiens (Human)) | BDBM50279929 ((2Z,6E,10E,14E)-6,11,15,19-Tetramethyl-2-(4-methyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound was measured against partially purified pig liver Squalene epoxidase (SE). | Bioorg Med Chem Lett 1: 227-232 (1991) Article DOI: 10.1016/S0960-894X(00)80258-9 BindingDB Entry DOI: 10.7270/Q27S7NP6 | |||||||||||
More data for this Ligand-Target Pair |