BDBM50279943 CHEMBL4160479

SMILES: CSC(=S)N\N=C\c1ccccn1

InChI Key: InChIKey=YLAWGUKUAFQSDH-UXBLZVDNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystathionine gamma-lyase (Homo sapiens (Human))	BDBM50279943 (CHEMBL4160479) Show SMILES CSC(=S)N\N=C\c1ccccn1 Show InChI InChI=1S/C8H9N3S2/c1-13-8(12)11-10-6-7-4-2-3-5-9-7/h2-6H,1H3,(H,11,12)/b10-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...				ACS Med Chem Lett 8: 1241-1245 (2017) Article DOI: 10.1021/acsmedchemlett.7b00313 BindingDB Entry DOI: 10.7270/Q2N300GT
					More data for this Ligand-Target Pair