BDBM50280195 1-(2-Chloro-phenyl)-tetrahydro-pyridazin-3-one::CHEMBL27410

SMILES: Clc1ccccc1N1CCCC(=O)N1

InChI Key: InChIKey=USBDJQWXUWOUBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50280195 (1-(2-Chloro-phenyl)-tetrahydro-pyridazin-3-one | C...) Show SMILES Clc1ccccc1N1CCCC(=O)N1 Show InChI InChI=1S/C10H11ClN2O/c11-8-4-1-2-5-9(8)13-7-3-6-10(14)12-13/h1-2,4-5H,3,6-7H2,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair