BDBM50280248 1-Methyl-4-((E)-2-naphthalen-1-yl-vinyl)-pyridinium; iodide::1-Methyl-4-(2-naphthalen-1-yl-vinyl)-pyridinium; iodide::CHEMBL106212::CHEMBL167967::CHEMBL282920

SMILES: C[n+]1ccc(\C=C\c2cccc3ccccc23)cc1

InChI Key: InChIKey=FJFKCRZPKGCGJE-MDZDMXLPSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50280248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Choline acetylase (Gallus gallus)	BDBM50280248 (1-Methyl-4-((E)-2-naphthalen-1-yl-vinyl)-pyridiniu...) Show SMILES C[n+]1ccc(\C=C\c2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H16N/c1-19-13-11-15(12-14-19)9-10-17-7-4-6-16-5-2-3-8-18(16)17/h2-14H,1H3/q+1/b10-9+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibitory activity against chick optic lobe choline acetyltransferase (ChAT)				Bioorg Med Chem Lett 2: 1493-1496 (1992) Article DOI: 10.1016/S0960-894X(00)80415-1 BindingDB Entry DOI: 10.7270/Q2QN66PD
					More data for this Ligand-Target Pair
Choline acetylase (Homo sapiens (Human))	BDBM50280248 (1-Methyl-4-((E)-2-naphthalen-1-yl-vinyl)-pyridiniu...) Show SMILES C[n+]1ccc(\C=C\c2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H16N/c1-19-13-11-15(12-14-19)9-10-17-7-4-6-16-5-2-3-8-18(16)17/h2-14H,1H3/q+1/b10-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Choline Acetyltransferase				J Med Chem 37: 3128-31 (1994) BindingDB Entry DOI: 10.7270/Q25M66X7
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50280248 (1-Methyl-4-((E)-2-naphthalen-1-yl-vinyl)-pyridiniu...) Show SMILES C[n+]1ccc(\C=C\c2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H16N/c1-19-13-11-15(12-14-19)9-10-17-7-4-6-16-5-2-3-8-18(16)17/h2-14H,1H3/q+1/b10-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Dynamac Corporation Curated by ChEMBL					Assay Description Inhibitory activity against acetylcholinetransferase (AChE) enzyme				J Med Chem 31: 807-14 (1988) BindingDB Entry DOI: 10.7270/Q24X590S
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50280248 (1-Methyl-4-((E)-2-naphthalen-1-yl-vinyl)-pyridiniu...) Show SMILES C[n+]1ccc(\C=C\c2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H16N/c1-19-13-11-15(12-14-19)9-10-17-7-4-6-16-5-2-3-8-18(16)17/h2-14H,1H3/q+1/b10-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase (AChE) activity				J Med Chem 31: 117-21 (1988) BindingDB Entry DOI: 10.7270/Q2XD12VJ
					More data for this Ligand-Target Pair
Choline acetylase (Homo sapiens (Human))	BDBM50280248 (1-Methyl-4-((E)-2-naphthalen-1-yl-vinyl)-pyridiniu...) Show SMILES C[n+]1ccc(\C=C\c2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H16N/c1-19-13-11-15(12-14-19)9-10-17-7-4-6-16-5-2-3-8-18(16)17/h2-14H,1H3/q+1/b10-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Dynamac Corporation Curated by ChEMBL					Assay Description Inhibition of choline acetyltransferase (CAT) enzyme				J Med Chem 31: 807-14 (1988) BindingDB Entry DOI: 10.7270/Q24X590S
					More data for this Ligand-Target Pair
Choline Acetyltransferase (RAT)	BDBM50280248 (1-Methyl-4-((E)-2-naphthalen-1-yl-vinyl)-pyridiniu...) Show SMILES C[n+]1ccc(\C=C\c2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H16N/c1-19-13-11-15(12-14-19)9-10-17-7-4-6-16-5-2-3-8-18(16)17/h2-14H,1H3/q+1/b10-9+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of choline acetyltransferase (ChAT) activity				J Med Chem 31: 117-21 (1988) BindingDB Entry DOI: 10.7270/Q2XD12VJ
					More data for this Ligand-Target Pair