BDBM50280294 3-[1-(4-Chloro-benzyl)-3-methyl-5-(5-phenyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid::CHEMBL297661

SMILES: Cc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc(cn3)-c3ccccc3)cc12

InChI Key: InChIKey=BKEIFYFYOIQSIO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50280294 (3-[1-(4-Chloro-benzyl)-3-methyl-5-(5-phenyl-pyridi...) Show SMILES Cc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc(cn3)-c3ccccc3)cc12 Show InChI InChI=1S/C33H31ClN2O3/c1-22-29-17-28(39-21-27-14-11-25(19-35-27)24-7-5-4-6-8-24)15-16-30(29)36(20-23-9-12-26(34)13-10-23)31(22)18-33(2,3)32(37)38/h4-17,19H,18,20-21H2,1-3H3,(H,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its inhibitory activity against 5-lipoxygenase in rat.				Bioorg Med Chem Lett 2: 1699-1702 (1992) Article DOI: 10.1016/S0960-894X(00)80459-X BindingDB Entry DOI: 10.7270/Q29C6XB4
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50280294 (3-[1-(4-Chloro-benzyl)-3-methyl-5-(5-phenyl-pyridi...) Show SMILES Cc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc(cn3)-c3ccccc3)cc12 Show InChI InChI=1S/C33H31ClN2O3/c1-22-29-17-28(39-21-27-14-11-25(19-35-27)24-7-5-4-6-8-24)15-16-30(29)36(20-23-9-12-26(34)13-10-23)31(22)18-33(2,3)32(37)38/h4-17,19H,18,20-21H2,1-3H3,(H,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its binding activity towards 5-lipoxygenase activating protein (FLAP)				Bioorg Med Chem Lett 2: 1699-1702 (1992) Article DOI: 10.1016/S0960-894X(00)80459-X BindingDB Entry DOI: 10.7270/Q29C6XB4
					More data for this Ligand-Target Pair