BDBM50280304 8-Ethyl-3-isopropyl-8H-1,2,3a,7,8,9-hexaaza-dibenzo[e,h]azulene::CHEMBL296773

SMILES: CCN1c2ncccc2-c2nnc(C(C)C)n2-c2cccnc12

InChI Key: InChIKey=NPEBEORKTTZTHX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50280304 (8-Ethyl-3-isopropyl-8H-1,2,3a,7,8,9-hexaaza-dibenz...) Show SMILES CCN1c2ncccc2-c2nnc(C(C)C)n2-c2cccnc12 Show InChI InChI=1S/C17H18N6/c1-4-22-15-12(7-5-9-18-15)16-21-20-14(11(2)3)23(16)13-8-6-10-19-17(13)22/h5-11H,4H2,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit HIV-1 IIIB reverse transcriptase catalyzed incorporation of tritiated thymidine triphosphate onto a biotinylated rN.dN template pr...				Bioorg Med Chem Lett 2: 1745-1750 (1992) Article DOI: 10.1016/S0960-894X(00)80468-0 BindingDB Entry DOI: 10.7270/Q2X63MW9
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50280304 (8-Ethyl-3-isopropyl-8H-1,2,3a,7,8,9-hexaaza-dibenz...) Show SMILES CCN1c2ncccc2-c2nnc(C(C)C)n2-c2cccnc12 Show InChI InChI=1S/C17H18N6/c1-4-22-15-12(7-5-9-18-15)16-21-20-14(11(2)3)23(16)13-8-6-10-19-17(13)22/h5-11H,4H2,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit HIV-1 IIIB reverse transcriptase catalyzed incorporation of tritiated thymidine triphosphate onto a biotinylated rA.dT template pr...				Bioorg Med Chem Lett 2: 1745-1750 (1992) Article DOI: 10.1016/S0960-894X(00)80468-0 BindingDB Entry DOI: 10.7270/Q2X63MW9
					More data for this Ligand-Target Pair