BDBM50280338 2-((S)-3-Amino-5-methyl-2-oxo-hexyl)-isoindole-1,3-dione; hydrochloride::CHEMBL542119
SMILES: CC(C)C[C@H](N)C(=O)CN1C(=O)c2ccccc2C1=O
InChI Key: InChIKey=VBVVFXXHFOCAJY-LBPRGKRZSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukocyte elastase (Homo sapiens (Human)) | BDBM50280338 (2-((S)-3-Amino-5-methyl-2-oxo-hexyl)-isoindole-1,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for the inhibition of human leukocyte elastase (HLE) | Bioorg Med Chem Lett 2: 175-180 (1992) Article DOI: 10.1016/S0960-894X(01)80445-5 BindingDB Entry DOI: 10.7270/Q2HX1CK4 | |||||||||||
More data for this Ligand-Target Pair |