BDBM50280369 CHEMBL4169114

SMILES: CCOc1ccc(cc1OC)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1

InChI Key: InChIKey=YVBPGGPLSRCXIM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 7 (mGlu7) (Rattus norvegicus (Rat))	BDBM50280369 (CHEMBL4169114) Show SMILES CCOc1ccc(cc1OC)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H17F3N4O4/c1-3-29-16-7-4-12(8-17(16)28-2)18(27)25-14-9-13(30-19(20,21)22)5-6-15(14)26-11-23-10-24-26/h4-11H,3H2,1-2H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats.				ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (mGlu7) (Rattus norvegicus (Rat))	BDBM50280369 (CHEMBL4169114) Show SMILES CCOc1ccc(cc1OC)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H17F3N4O4/c1-3-29-16-7-4-12(8-17(16)28-2)18(27)25-14-9-13(30-19(20,21)22)5-6-15(14)26-11-23-10-24-26/h4-11H,3H2,1-2H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin I converting enzyme of rats.				ACS Med Chem Lett 8: 1326-1330 (2017) Article DOI: 10.1021/acsmedchemlett.7b00429 BindingDB Entry DOI: 10.7270/Q25X2CG2
					More data for this Ligand-Target Pair