BDBM50280539 2,8-Dimethyl-1-oxa-3-thia-8-aza-spiro[4.5]decane::CHEMBL424360

SMILES: CC1OC2(CS1)CCN(C)CC2

InChI Key: InChIKey=SEAOIMROVSRHCL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280539 (2,8-Dimethyl-1-oxa-3-thia-8-aza-spiro[4.5]decane |...) Show SMILES CC1OC2(CS1)CCN(C)CC2 Show InChI InChI=1S/C9H17NOS/c1-8-11-9(7-12-8)3-5-10(2)6-4-9/h8H,3-7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for its muscarinic m1 receptor agonist potency in the ileum model as a functional measure of peripheral muscarinic m1 re...				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280539 (2,8-Dimethyl-1-oxa-3-thia-8-aza-spiro[4.5]decane |...) Show SMILES CC1OC2(CS1)CCN(C)CC2 Show InChI InChI=1S/C9H17NOS/c1-8-11-9(7-12-8)3-5-10(2)6-4-9/h8H,3-7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair