BDBM50280644 2-[2-(1-Benzyl-piperidin-4-yl)-eth-(E)-ylidene]-5,6-dimethoxy-indan-1-one::CHEMBL354850

SMILES: COc1cc2CC(=CCC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC

InChI Key: InChIKey=UFDYWDFEWUZQKH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Mus musculus (mouse))	BDBM50280644 (2-[2-(1-Benzyl-piperidin-4-yl)-eth-(E)-ylidene]-5,...) Show SMILES COc1cc2CC(=CCC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC |w:7.7| Show InChI InChI=1S/C25H29NO3/c1-28-23-15-21-14-20(25(27)22(21)16-24(23)29-2)9-8-18-10-12-26(13-11-18)17-19-6-4-3-5-7-19/h3-7,9,15-16,18H,8,10-14,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Acetylcholinesterase activity in mouse brain homogenate				Bioorg Med Chem Lett 2: 871-876 (1992) Article DOI: 10.1016/S0960-894X(00)80547-8 BindingDB Entry DOI: 10.7270/Q21R6QDV
					More data for this Ligand-Target Pair