BDBM50280703 CHEMBL278210::Sodium; 2-{1-[3-(7-chloro-quinolin-2-ylmethoxy)-phenyl]-3-[2-(1H-tetrazol-5-yl)-phenyl]-propylsulfanylmethyl}-butyrate

SMILES: CCC(CSC(CCc1ccccc1-c1nnn[nH]1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O

InChI Key: InChIKey=QVCMBMYBGUPCRP-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280703 (CHEMBL278210 | Sodium; 2-{1-[3-(7-chloro-quinolin-...) Show SMILES CCC(CSC(CCc1ccccc1-c1nnn[nH]1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C31H30ClN5O3S/c1-2-20(31(38)39)19-41-29(15-12-21-6-3-4-9-27(21)30-34-36-37-35-30)23-7-5-8-26(16-23)40-18-25-14-11-22-10-13-24(32)17-28(22)33-25/h3-11,13-14,16-17,20,29H,2,12,15,18-19H2,1H3,(H,38,39)(H,34,35,36,37)/p-1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair