BDBM50280713 CHEMBL15232::Sodium; 2-{1-[3-(7-chloro-quinolin-2-ylmethoxy)-phenyl]-3-[2-(1-methyl-1H-tetrazol-5-yl)-phenyl]-propylsulfanylmethyl}-butyrate

SMILES: CCC(CSC(CCc1ccccc1-c1nnnn1C)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O

InChI Key: InChIKey=KFPTUNJJKOMORB-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280713 (CHEMBL15232 | Sodium; 2-{1-[3-(7-chloro-quinolin-2...) Show SMILES CCC(CSC(CCc1ccccc1-c1nnnn1C)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C32H32ClN5O3S/c1-3-21(32(39)40)20-42-30(16-13-22-7-4-5-10-28(22)31-35-36-37-38(31)2)24-8-6-9-27(17-24)41-19-26-15-12-23-11-14-25(33)18-29(23)34-26/h4-12,14-15,17-18,21,30H,3,13,16,19-20H2,1-2H3,(H,39,40)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair