BDBM50281082 (Hydroxy-methoxy-phosphorylmethyl)-((3E,7E)-4,8,12-trimethyl-trideca-3,7,11-trienyl)-phosphinic acid anion::(Hydroxy-methoxy-phosphorylmethyl)-(4,8,12-trimethyl-trideca-3,7,11-trienyl)-phosphinic acid anion

SMILES: [#6]-[#8]P([#8-])(=O)[#6]P([#8-])(=O)[#6]=[#6]-[#6]-[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]

InChI Key: InChIKey=LQQHFDLZPRVXSW-XKQXORHHSA-L

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Squalene synthase (Rattus norvegicus)	BDBM50281082 ((Hydroxy-methoxy-phosphorylmethyl)-((3E,7E)-4,8,12...) Show SMILES [#6]-[#8]P([#8-])(=O)[#6]P([#8-])(=O)[#6]=[#6]-[#6]-[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6] |w:10.10| Show InChI InChI=1S/C18H34O5P2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-24(19,20)15-25(21,22)23-5/h8-9,11,14,18H,6-7,10,12-13,15H2,1-5H3,(H,19,20)(H,21,22)/p-2/b14-8?,17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.77E+5	n/a	n/a	n/a	n/a	n/a	n/a
Squibb Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of squalene synthetase was determined in rat liver microsomes				J Med Chem 31: 1869-71 (1988) BindingDB Entry DOI: 10.7270/Q2NZ88T8
					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50281082 ((Hydroxy-methoxy-phosphorylmethyl)-((3E,7E)-4,8,12...) Show SMILES [#6]-[#8]P([#8-])(=O)[#6]P([#8-])(=O)[#6]=[#6]-[#6]-[#6](-[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6] |w:10.10| Show InChI InChI=1S/C18H34O5P2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-24(19,20)15-25(21,22)23-5/h8-9,11,14,18H,6-7,10,12-13,15H2,1-5H3,(H,19,20)(H,21,22)/p-2/b14-8?,17-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	1.77E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity measured against rat squalene synthase(SQS) enzyme				Bioorg Med Chem Lett 3: 2541-2546 (1993) Article DOI: 10.1016/S0960-894X(01)80713-7 BindingDB Entry DOI: 10.7270/Q26Q1XQP
					More data for this Ligand-Target Pair